The five-year rate of heart disease death or nonfatal myocardial infarction was lower in patients initially provided CTA imaging (n= 48 [2.3%]) than in patients given standard evaluation (n= 81 [3.9%]), providing investigators a hazard ratio of 0.59 (95% CI; 0.41-0.84; P = .004).
Patients provided CTAs reported similar rates of invasive coronary angiography to standard-care patients (491 vs 502; HR 1.00; 95% CI; 0.88-1.13), as well as in coronary revascularization (279 vs 267; HR 1.07; 95% CI; 0.91-1.27). Investigators noted this difference is improved from earlier follow-up analyses, when patients provided CTAs reported notably greater rates in both procedures.
That said, preventive therapies were more frequently initiated in patients provided CTAs (OR 1.40; 95% CI; 1.19-1.65), as were antianginal therapies (OR 1.27; 95% CI; 1.05-1.54). Newby noted that there's often a "big to-do" in the idea of providing a patient preventive aspirin therapy on top of statins. He advocated against it, but noted it has its place in coronary treatment.