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Tuesday, October 10, 2017

Quercetin alleviates generalized hyperalgesia in mice with induced adenomyosis

The results demonstrated that treatment with quercetin improved the generalized hyperalgesia by extending the hotplate response latency, reduced myometrial infiltration and decreased the expression levels Trpv‑1, p‑p38 and p‑ERK in dorsal root ganglion neurons. The results indicated that quercetin decreases the incidence of hyperalgesia in mice with tamoxifen‑induced adenomyosis, and the potential mechanism is through reduced central sensitization, which may be a promising treatment for adenomyosis.

https://www.ncbi.nlm.nih.gov/m/pubmed/28849202/?i=3&from=Tamoxifen%20endometrial

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