Women undergoing infertility treatment who consumed more high-pesticide residue foods had a lower likelihood of clinical pregnancy and live birth compared with their peers, a new prospective epidemiological study showed.
Compared with women in the lowest quartile of high-pesticide residue fruits and vegetable intake (<1.0 servings/day), women in the highest quartile (≥2.3 servings/day) had an 18% lower probability of achieving a clinical pregnancy (95% confidence interval [CI], 5% - 30%) and a 26% lower probability of having a live birth (95% CI, 13% - 37%).
Moreover, substituting just one serving/day of low-pesticide residue produce for one serving/day of high-pesticide residue produce was associated with 79% higher odds of clinical pregnancy (95% CI, 11% -188%) and 88% higher odds of live birth (95% CI, 16% - 205%).
"These data suggest that dietary pesticide exposure within the range of typical human exposure may be associated with adverse reproductive consequences," write Yu-Han Chiu, MD, ScD, from the Department of Nutrition and the Department of Epidemiology at Harvard T.H. Chan School of Public Health in Boston, Massachusetts, and colleagues.