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Tuesday, November 15, 2016

Non-nutritive sweetener effects may contribute to insulin resistance in consumers with obesity

Sucralose, a no-calorie sweetener widely used in beverages, may adversely affect glucose metabolism in consumers with obesity, according to a presenter here.

"There seem to be differential effects of sucralose on glucose metabolism in normal-weight people and in people with obesity, so previous findings in lean subjects cannot be extrapolated to what will be the effects of sucralose in subjects with obesity (and vice versa)," Marta Yanina Pepino De Gruev, PhD, assistant professor in food science and human nutrition at the University of Illinois in Urbana, told Endocrine Today. "Clinicians may find surprising that sucralose is not metabolically inert, as generally thought, at least for people with obesity."


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