Dr. Bray Links

Friday, April 15, 2016

Adult Growth Hormone Deficiency

A person who has too little adult growth hormone will have symptoms that include:

  •     A higher level of body fat, especially around the waist
  •     Anxiety and depression
  •     Decreased sexual function and interest
  •     Fatigue
  •     Feelings of being isolated from other people
  •     Greater sensitivity to heat and cold
  •     Less muscle (lean body mass)
  •     Less strength, stamina and ability to exercise without taking a rest
  •     Reduced bone density and a tendency to have more bone fractures as they get older
  •     Changes in the make up of the blood cholesterol.

People with adult growth hormone deficiency have higher than normal levels of low-density lipoproteins in comparison to their high density lipoproteins. They also tend to have higher triglyceride levels. (Triglycerides are another type of fat that circulates in the blood and contributes to blocked blood vessels.)


High IGF-1 from dietary ingestion inhibits the hypothalamus through decreased GHRH and Somatostatin. Long-term effects of exogenous IGF-1 is suppression of endogenous growth hormone. So ... how much milk did you drink when milk was derived from rBGH or rBST treated cows?


Consumption of cow's milk and cow's milk protein result in changes of the hormonal axis of insulin, growth hormone and insulin-like growth factor-1(IGF-1) in humans. Milk consumption raises IGF-1 serum levels in the perinatal period, adolescence and adulthood. During puberty with the physiological onset of increased secretion of growth hormone, IGF-1 serum levels increase and are further enhanced by milk consumption. IGF-1 is a potent mitogen; after binding to its receptor in various tissues, it induces cell proliferation and inhibits apoptosis. Keratinocytes and sebocytes, as well as the androgen-synthesizing adrenals and gonads, are stimulated by IGF-1. The epidemic incidence of adolescent acne in Western milk-consuming societies can be explained by the increased insulin- and IGF-1-stimulation of sebaceous glands mediated by milk consumption. Acne can be regarded as a model for chronic Western diseases with pathologically increased IGF-1-stimulation. Many other organs, such as the thymus, bones, all glands, and vascular smooth muscle cells as well as neurons are subject to this abnormally increased hormonal stimulation. The milk-induced change of the IGF-1-axis most likely contributes to the development of fetal macrosomia, induction of atopy, accelerated linear growth, atherosclerosis, carcinogenesis and neurodegenerative diseases. Observations of molecular biology are supported by epidemiologic data and unmask milk consumption as a promoter of chronic diseases of Western societies.


No comments:

Post a Comment

Note: Only a member of this blog may post a comment.