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Friday, October 16, 2015

Carotenoid-Rich Diet May Protect Against Advanced Eye Disease

When the researchers compared extreme quintiles of predicted plasma lutein/zeaxanthin score, they found an approximately 40% reduced risk for advanced AMD (relative risk = 0.59; 95% confidence interval, 0.48 - 0.73; P for trend < .001).

Similarly, "[p]redicted plasma carotenoid scores for other carotenoids, including β-cryptoxanthin, α-carotene, and β-carotene were associated with a 25% to 35% lower risk of advanced AMD," the authors write.

The investigators observed no association between the outcome of intermediate AMD and any of the predicted plasma carotenoid scores, suggesting intake of carotenoids has an effect on AMD progression, rather than initiation.

"Lutein and zeaxanthin form macular pigments that may protect against AMD by reducing oxidative stress, absorbing blue light, and stabilizing cell membranes," the authors explain.

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