Dr. Bray Links

Tuesday, September 22, 2015

Recent Whooping Cough Increase May Come From a Different Species

The recent increase in outbreaks of whooping cough might not be related to the common Bordetella pertussis pathogen, but instead to a lesser-known but related species, data from a recent Minnesota outbreak suggest.

Although Bordetella parapertussis has been shown to cause similar clinical manifestations, vaccination against B pertussis does not protect against B parapertussis, said Vytas Karalius, MPH, who is a medical student at the Mayo Clinic in Rochester, Minnesota.

"Symptoms alone may not enable a distinction between the two, which supports testing for both when a patient presents with whooping cough symptoms," Karalius explained here at the Interscience Conference of Antimicrobial Agents and Chemotherapy 2015.

Karalius and his colleagues conducted an analysis of all patients at the Mayo Clinic tested for both B pertussis and B parapertussis from 2012 to 2014. All tests were done using nasopharyngeal swabs and real-time polymerase chain reaction (PCR) assays.


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