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Wednesday, July 15, 2015

Antidepressant/NSAID Combo Linked to Brain Bleed Risk


The combination of antidepressants and nonsteroidal anti-inflammatory drugs (NSAIDS) is linked to an early increased risk for intracranial hemorrhage, regardless of the type of NSAID or antidepressant, new research shows.

"The take-home message for clinicians is that special attention should be paid [to] antidepressant users when they start an NSAID prescription," coauthor Byung-Joo Park, MD, MPH, PhD, told Medscape Medical News.

"Monitoring bleeding risk is particularly needed at the initial combined use of both medicines," added Dr Park, who is a professor in the Seoul National University College of Medicine's Department of Preventive Medicine, in Korea.

The study was published online July 14 in the BMJ.

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