There is currently growing evidence that vegetable oils and animals fed with inflammatory oil products (for example grain-fed chickens or corn-fed cows) have high omega-6 tendencies which raise YOUR linoleic acid and arachidonic acid. In doing so, it not only creates problematic inflammation, but puts our body into winter hibernation "mode". Matt Stone (links below) is a Paleo skeptic.
"Thirteen-lined ground squirrels (Spermophilus tridecemlineatus) were fed one of four isocaloric, isolipemic diets containing 16, 22, 35 or 55 mg linoleic acid (18:2n-6) per gram. Mitochondrial properties were compared between hibernating and summer active states, and between diet groups. As in other studies, state 3 respiration was significantly reduced in hibernation, but only in animals fed the 22 mg g(-1) 18:2 diet. In the other diet groups, there was no difference in state 3 respiration between the hibernating and summer active groups. In the 22 mg g(-1) 18:2 diet group, there was no difference in mitochondrial proton conductance between hibernating and summer active animals, again in agreement with earlier studies. However, for all other diet groups, mitochondrial proton conductance was significantly reduced during hibernation. Mitochondrial phospholipid fatty acids changed significantly with hibernation, including increases in unsaturation indices and n-6/n-3, but no differences were found among diet groups. Mitochondrial proton conductance in hibernation showed a positive correlation with the content of linoleic acid (18:2) and arachidonic acid (20:4) in mitochondrial phospholipids. Lipid peroxidation was higher in mitochondria from hibernating animals, probably due to higher unsaturation, but there was no effect of dietary 18:2 on this pattern. Despite the dietary effects on mitochondrial metabolism, all animals hibernated with no differences in bout durations, body temperatures or whole-animal metabolic rates among the diet groups. The reduced mitochondrial proton leak in the 15, 35 and 55 mg g(-1) 18:2 diet groups might compensate for the inability to suppress respiration, permitting whole-animal energy savings over the hibernation season."
"Solving the Paleo Equation: Stress, Nutrition, Exercise, Sleep is the ultimate guide to customizing your diet and lifestyle practices to your unique physical and metabolic needs. You'll learn how to maximize your health practices and minimize your time and effort—no more driving yourself to exhaustion in hardcore fitness classes. No more strict, unsustainable, and impractical approaches to nutrition, either. Solving the Paleo Equation will help you not only avoid the ravages of adrenal fatigue, low metabolism, dwindling sex drive, and sleep problems—all-too-common consequences of overzealous workout regimes—it will help you rehabilitate from the unhealthful "health" protocols you've pursued in the past."
The home of Dr. Garrett Smith and renowned metabolism expert Matt Stone.